Participants will be required to attend 4 nights and 5 days in-house stay and a follow-up visit on Day 8.
- Healthy Males and Females aged 18 to 75 years old.
- Participants must have a Body Mass Index (BMI) of 19-32kg/m2.
- Participants must have moderate to severe renal impairment.
- Participants should be non-smokers.