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Healthy Volunteer Studies

LE180604 | Heart Disease Study

Help us test a new treatment for dyslipidaemia! Otherwise known as abnormal levels of lipids in the blood (e.g. cholesterol and triglycerides). Untreated it can lead to heart disease and many other serious conditions, due to a build-up of these lipids in arteries.

You Get $3060! 

(remuneration based on completion of in-house stay and all follow-up appointments)

3 nights and 4 days with 11 follow-up visits.

EXAMPLE TIMELINES LE180604  COHORT 1
In-house StayCheck-In15-Jan
Check-Out18-Jan
AppointmentsDay 319-Jan
Day 824-Jan
Day 1531-Jan
Day 2207-Feb
Day 2914-Feb
Day 4328-Feb
Day 5714-Mar
Day 7128-Mar
Day 8511-Apr
Day 9925-Apr
Day 11309-May
  • Healthy Males and Females between the ages of 18 and 65
  • BMI must be between 19 – 37 kg/m
  • Participants will be required to have elevated triglycerides & LDL-C (found in cholesterol checks) this is tested in screening or we can look at any recent results that you provide
  • Must be on a stable diet for at least 4 weeks and over the duration of the study
  • Must not have any clinically significant illness or disease
  • Must be non-smokers (Max 2 cigarettes per month within the previous 6 months)
  • Participants must be willing to consume a high fat & high carbohydrate meal prior to dose (e.g. fried bacon, fried eggs, full fat milk)
  • Must be willing to provide stool samples

APPLY NOW

 

 

LE180802 | Macular Degeneration Study

Help us trial a new investigational treatment for dry age-related macular degeneration (AMD) and juvenile onset macular degeneration, known as Stargardt disease (STGD). 

You Get $1600! 

(remuneration based on completion of in-house stay and all follow-up appointments)

 Appointment Schedule

5 day, 4 nights stay, 1 appointment and a follow up phone call

CohortIn-HousePhone CallAppointment
Check-In Day-1Dosing Day 1Check-Out Day 4Day 6Day 8
2.102-Feb03-Feb06-Feb08-Feb11-Feb
2.204-Feb05-Feb08-Feb10-Feb11-Feb
  • Healthy Males and Females, aged between 18 and 65
  • Females must be of Non-Childbearing Potential (either Surgically Sterile or Postmenopausal)
  • Body Mass Index (BMI) between 18 – 30 kg/m2
  • Must be free from any clinically significant illness or disease
  • Participants must be non-smokers (Have not used any nicotine containing products in the last 28 days)
  • Participants must not have a history any severe reactions to medications
  • Participants must not have a history of Retinal Macular Edema or Stargardt Disease

 APPLY NOW

 

 

LE180803 | Alzheimer’s Disease Study

Help us trial a new treatment for Alzheimer’s Disease!

Alzheimer’s Disease is one of the leading causes of death in Australia, second only to Ischemic Heart Disease. It is the most common cause of dementia and accounts for 60 percent to 80 percent of dementia cases. In Australia, more than 425,000 people are living with dementia. Without a medical breakthrough, the number of people with dementia is expected to be over 1,100,000 by 2056. 

There is currently no cure for Alzheimer’s Disease. The medications currently available provide short term symptomatic treatment and there are no drugs available that can directly treat the disease. 

You Get $1400! 

Visit Schedule

6 appointments with additional phone calls as required.

CohortAppointment 123456
107-Feb21-Feb07-Mar04-Apr02-May30-May
208-Feb22-Feb08-Mar05-Apr03-May31-May
313-Feb27-Feb13-Mar10-Apr08-May05-Jun
414-Feb28-Feb14-Mar11-Apr09-May06-Jun
515-Feb01-Mar15-Mar12-Apr10-May07-Jun
618-Feb05-Mar18-Mar15-Apr13-May10-Jun
719-Feb05-Mar19-Mar16-Apr14-May11-Jun
820-Feb06-Mar20-Mar17-Apr15-May12-Jun
925-Feb11-Mar25-Mar23-Apr20-May17-Jun
1026-Feb12-Mar26-Mar23-Apr21-May18-Jun
1127-Feb13-Mar27-Mar24-Apr22-May 19-Jun
  • Healthy Males and Females
  • Ages of 50 – 75
  • Must be free from any medical conditions which may cause neuropathy e.g. diabetes
  • Must be free from any medical conditions related to the hypothalamus, pituitary or adrenal glands
  • Must be willing to provide a 3mm skin biopsy
  • Participants must be willing to complete a Daily Drug Intake Diary.
  • Volunteers must be free from any clinically significant illness

 APPLY NOW

 

LE181003 | PKU Study

 

Help us trial a new treatment for phenylketonuria (PKU) and hyperphenylalaninemia (HPA). PKU is an inherited genetic condition that causes an increase in the levels of a substance called phenylalanine in the blood. If PKU is not treated, phenylalanine can build up to harmful levels in the body, leading to HPA and causing intellectual disability and other serious health problems.

You Get $900! 

Visit Schedule

2 nights and 3 days with 2 follow-up visits.

 

Cohort

 

In-House PeriodFollow-Up Visits

Check-in

D -1

Check-out

D2

D8D22
2 (ON HOLD)23-Jan25-Jan31-Jan14-Feb
3 (OPEN)10-Feb12-Feb18-Feb04-Mar
  • Healthy Males and Females between the ages of 18 and 55
  • BMI must be between 18 – 30 kg/m( > 50kg, < 100kg)
  • Volunteers must be free from any clinically significant illness
  • Must be non-smokers (Max 3 cigarettes in the last 6 months)
  • Participants must be willing to consume a standard meal prior to dosing (e.g. bread, cereal, milk and yogurt).
  • Must not have a history of food intolerance (E.g. gluten, lactose, dairy).
  • Must not have participated in our previous study LE17102

 APPLY NOW

 

LE180901 | Asthma Study

 

Help us research a medication for the treatment of Asthma!

You Get $5140! 

(this payment is based on completing all dates from one of the trial’s cohorts)

Visit Schedule

13 days in-house and 2 appointments

CohortIn-HouseAppointments
Check-In Day-1Check-Out Day 12Day 17Day 40
3.107-Jan19-Jan23-Jan16-Feb
3.214-Jan26-Jan01-Feb23-Feb
3.3 21-Jan 02-Feb 07-Feb 02-Mar
3.429-Jan 10-Feb15-Feb 10-Mar

  • Healthy Males and Females between the ages of 18 and 55
  • BMI must be between 18 – 35 kg/m2   
  • Must have diagnosis of mild asthma. (Documented evidence needed)
  • Must be non-smokers (smoked no more than 2 in the last 3 months)

APPLY NOW

LE180501 | Cardiovascular Disease Study

 

Help us test a new treatment for Cardiovascular Disease (CVD) and elevated plasma Lipoprotein(a) levels. Cardiovascular disease kills one Australian every 12 minutes (The Heart Foundation). Participating in this trial means you’ll be supporting world leading research into improving treatments.

You Get $2550! 

(remuneration based on completion of in-house stay and all follow-up appointments)

This Research is being run by a world leading expert in this area, Professor Gerald Watts.

 Example Visit Schedule

5 day stay with 11 appointments spread across 5 months 

LE180501 Study TimelineCOHORT 4 Group 1 COHORT 4 Group 2
In-HouseCheck-In04-Dec05-Dec
Check-Out08-Dec09-Dec
Follow upDay 711Dec12-Dec
Day 1519Dec20-Dec
Day 1822-Dec22-Dec
Day 2227-Dec27-Dec
Day 2903-Jan03-Jan
Day 4316-Jan17-Jan
Day 5730-Jan31-Jan
Day 7113-Feb14-Feb
Day 8527-Feb 28-Feb
Day 11327-Mar 28-Mar
Day 15508-May 09-May
  • Healthy Males and Females, aged between 18 and 60
  • Females must be of Non-Childbearing Potential (either Surgically Sterile or Postmenopausal)
  • Body Mass Index (BMI) between 18 – 32 kg/m2
  • Elevated plasma Lipoprotein(a) level ≥70 and ≤199nmol/L, confirmed by a pre-screen blood test
  • Not currently on any medications with the exception of Statin, lipid-lowering medications (for certain cohorts only)
  • Participants must be non-smokers (Have not used any nicotine containing products in the last 6 months)

APPLY NOW

 

LE180302 | Autoimmune Disease Study

 

Autoimmune diseases are a broad range of related diseases in which a person’s immune system produces an inappropriate response against its own cells, tissues and/or organs. This results in inflammation and damage. Help us research a medication for the treatment of Inflammatory Autoimmune Disease! 

You Get $4500! 

(this payment is based on completing all dates from one of the trial’s cohorts)

Visit Schedule

18 days in-house and 5 appointments

CohortIn-HouseAppointments
Check-In

Day-1

Check-Out

Day 17

Day 18Day 19Day 20Day 21Day 22
918-Feb07-Mar08-Mar09-Mar10-Mar11-Mar12-Mar
  • Healthy Males and Females between the ages of 18 and 55
  • BMI must be between 18 – 31 kg/m2   
  • Volunteers must be free from any clinically significant illness
  • Happy to consume Gelatin Capsules ingredients containing bovine and/or porcine origin.
  • Must be non-smokers (for at least the last 6 months)

APPLY NOW

 

 

LE180706 | DMTS Study

ON HOLD

Help us trial a new investigational treatment designed to be used in the management of post-operative pain. Dexmedetomidine is a sedative drug currently approved in Australia by the Therapeutic Goods Administration (TGA) for intravenous use. It is used in hospital settings to sedate patients prior to and during surgical procedures. We are investigating a transdermal drug delivery system (skin patch) to be used as an alternative to intravenous dosing to reduce post-operative pain.

You Get $2140! 

Visit Schedule

One in-house stay of 7 nights and 8 days

CohortIn-House Period 
Check-in D -1Check-out D7
124-Feb 03-Mar

 

  • Healthy Males and Females
  • Between 18 – 60 years of age
  • Body Mass Index (BMI) must be between 18.0 – 38.0 kg/m2 
  • Must be non-smokers (Max 2 cigarettes per month within the previous 6 months)
  • Must not have any existing chronic skin conditions (e.g. psoriasis, eczema, acne, rosacea), skin allergies, or sensitivities that could prevent the ability to wear a transdermal patch.
  • Must not have any scars, tattoos, burns, wounds, or excessive hair on the upper portion of the arm.
  • Must not have any clinically significant illness, disease, or severe allergies.
  • Must have a resting heart rate grater than 60 BPM

APPLY NOW

 

LE17124 | Hearing Loss Study

ON HOLD

Investigating a new treatment for children with cancer who suffer hearing loss as a result of exposure to chemotherapy drugs. It is estimated that, on average, about 750 children aged 0-14 years old are diagnosed with cancer each year in Australia (Cancer Council). Participating in this trial means you’ll be supporting world leading research into improving hearing loss treatments for these children.

You Get $2320! 

(This payment is based on completing the in-house stay and all scheduled appointments)

Visit Schedule

2 nights and 3 days with one follow up phone call and three in-house follow-up appointments

LE17124 STUDY TIMELINESCOH 2.1COH 2.2COH 2.3COH 2.4
In-HouseCheck-In20-Jan30-Jan03-Feb10-Feb
Check-Out22-Jan01-Feb05-Feb12-Feb
Follow UpDay 4 (phone call)24-Jan03-Feb07-Feb14-Feb
Day 828-Jan07-Feb11-Feb18-Feb
Day 1504-Feb14-Feb18-Feb25-Feb
Day 3019-Feb01-Mar05-Mar12-Mar

 

  • Healthy Males and Females, aged between 18 and 65
  • Body Mass Index (BMI) between 18 – 35 kg/m2
  • Normal hearing,  defined as ≤20 dB from 250 Hz to 8 kHz bilateral
  • No allergies to any local anesthetics (numbing medication)
  • Free from any clinically significant illness or disease as determined by their medical history.
  • Must be willing to attend a hearing test if eligible after first screening visit.

 

LL17035 | Malaria Study

Visit Schedule #Appointments Only

Participants will be required to attend 7 – 10 appointments. 

Part 1 Treatment (Week 1-52)Part 2 Follow-upPart 3 (Only if required)
Visit234567a7b8910
Week1412245264647689104
Hours2-323-43-43-43-43-41-21-21-2
Payment $ 490700810810210 210210

*Participants who complete the study up to Week 64 will receive in total  You Get *$2880! 

  • Healthy males and females between the ages of 18 and 55
  • Must agree to stay in contact with the study site for the duration of the study and up to Week 64 (Visit 7b). Have no current plans to move away from Perth for the duration of the study
  • Must maintain a diary throughout the study
  • No eye conditions or use of prescription eye drops

APPLY NOW

 

Patient Studies

LL180511 | Coeliac Study

Help us test a new investigational medication for Coeliac disease!

A gluten-free diet is the only current treatment for Coeliac disease. This study will research whether subcutaneous doses of the trial medication can target the immune response in people with Coeliac disease to protect them from the effects of gluten exposure.  

Visit Schedule

20 x appointments, 1 x phone call & daily diary entries/doses at-home over approximately 7 months.

Screening PeriodDosing PeriodMaintenance PeriodFollow-Up
Appointments at Linear11171
At-home Questionnaire &/or Dosing319
Phone Call1
Approximate Appointment Time (At Linear)9 hrs1 x 7hrs & 10 x 1hr4 x 5-6hrs, 2 x 6hrs, 1 x 1-2hrs1 x 1-2hrs

 

Inclusion Criteria

  • Healthy Males and Females between the ages of 18 and 70
  • Have a diagnosis of Coeliac Disease confirmed with documentation (intestinal biopsy).
  • Have maintained Gluten-free Diet (GFD) for at least 12 consecutive months prior to screening.
  • Willing to consume a moderate amount of gluten (approximately 6 g of gluten protein) once at the screening visit and at a maximum of two other time points for the study.

APPLY NOW