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Healthy Volunteer Studies

 

 

LE17102 | PKU STUDY 

Visit Schedule

2 nights and 3 days with 2 follow-up visits.

Cohort

In-House Period  Follow-Up Visits
Check-in

D -1

Check-out

D3

D8

D22

1

 03 July 05 July 11 July  25 July

2

 04 July  06 July  12 July  26 July

 

Participants will receive $900 (this payment is based on completing all dates from one of the trial’s cohorts).

Testing a medication for the treatment of  phenylketonuria (PKU) and hyperphenylalaninemia (HPA).

Inclusion Criteria

  • Healthy Males and Females between the ages of 18 and 55
  • BMI must be between 18 – 30 kg/m( > 50kg, < 100kg)
  • Volunteers must be free from any clinically significant illness
  • Must be non-smokers (Max 3 cigarettes in the last 6 months)
  • Participants must be willing to consume a standard meal prior to dose (e.g. bread, cereal, milk and yogurt).
  • Must not have a history of food intolerance (E.g. gluten, lactose, dairy).

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LE17122 | HAE Study

COMING SOON | Visit Schedule

3 nights and 4 days with 1 follow-up visit 

Please note: These dates are to be confirmed.

Cohort Confinement Period 1

Follow-up Visit

Check-in

Day -1

Check-out

Day 2

Day 8
4 A 23 July 26 July 31 July
4 B 24 July 27 July 1 August

Participants will receive $1100 (this payment is based on completing all dates for this cohort).

Testing a medication for the treatment of a condition involving swelling (HAE).

Inclusion Criteria

  • Healthy Males between the ages of 18 and 55
  • BMI must be between 18 – 30 kg/m2
  • Must be free from any clinically significant illness or disease
  • Must be non-smokers (for at least the last 2 months)
  • Participants must be willing to refrain from strenuous exercise from 7 days prior to check-in until completion of the study.

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LE17113 | IBD STUDY PART 2

Visit Schedule

15 nights and 16 days with 1 follow-up visit.

Cohort In-House Period  Follow-Up Visit 
Check-in

D -1

Check-out

D15

D21
1-FULL 02-Jul 17-Jul 23-Jul
Cohort In-House Period  Follow-Up Visit 
Check-in

D -1

Check-out

D15

D21
2 30-Jul 14-Aug 20-Aug

Participants will receive $3760 (this payment is based on completing all of the cohorts dates).

Testing a medication for the treatment of inflammatory bowel disease (IBD) including ulcerative colitis and Crohn’s Disease.

Inclusion Criteria

  • Healthy Males between the ages of 18 and 45
  • BMI must be between 19 – 30 kg/m2
  • Must be free from any clinically significant illness or disease
  • Participants must not have used more than 10 nicotine products per day in the 3 months prior to the study.
  • Must not use any prescription medications within 30 days prior to Day 1
  • Participants must be willing to consume a standard meal prior to dose. (Not suitable for Vegans).

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LE180302 | Inflammatory Autoimmune Disease Study

ON HOLD | Visit Schedule

4 nights and 5 days with 5 follow-up visits.

Cohort In-House Period Follow-up Visits
Check-In

Day-1

Check-Out

Day 4

Day 5 Day 6 Day 7 Day 8 Day 9
2 | FULL 09-July 13-July 14-July 15-July 16-July 17-July 18-July

Participants will receive $1600 (this payment is based on completing all dates from one of the trial’s cohorts).

Testing a medication for the treatment of Inflammatory Autoimmune Disease.

Inclusion Criteria

  • Healthy Males and Females between the ages of 18 and 55
  • BMI must be between 18 – 31 kg/m2   
  • Volunteers must be free from any clinically significant illness
  • Must be non-smokers (for at least the last 6 months)

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LE180101 | STEMI Study

STUDY ON HOLD | Visit Schedule

3 nights and 4 days with 1 follow-up over the phone.

Please note: These dates are subject to change.

Cohort In-House Period Phone Follow-up
Check in

Day-1

Check out

Day 3

Day 7
1 TBC TBC TBC

 

Participants will receive $1000 (this payment is based on completing all dates from one of the trial’s cohorts).

Testing a medication being developed to treat patients with a serious type of heart attack known as ST-Elevation Myocardial Infarction (STEMI).

Inclusion Criteria

  • Healthy Males and Females between the ages of 18 and 50
  • BMI must be between 18 – 32 kg/m2
  • Volunteers must be free from any clinically significant illness
  • Must be non-smokers (Max 1-2 cigarettes in the last 6 months)

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LE17126 | Pain & Itch Relief

CURRENT COHORT IS FULL
Visit Schedule

3 nights and 4 days with 1 follow-up visit 

 

Cohort In-House Period  Follow-up Visit 
Check-in 
Day -1
Check out 
Day 3
Day 8
6 A | FULL  25-June 28-June 03-July
6 B | FULL  26-June 29-June 04-July

 

Participants will receive $1000 (this payment is based on completing all dates from one of the trial’s cohorts).

Testing a new analgesic (pain relief) and anti-pruritic (anti-itch) medication.

Inclusion Criteria

  • Healthy Males between the ages of 18 and 45
  • BMI must be between 18 – 30 kg/m2 
  • Must be free from any clinically significant illness or disease
  • Must be non-smokers (for at least the last 6 months)
  • Participants must not be heavy caffeine drinkers (more than five cups or glasses of caffeinated beverages per day)
  • Participant must not have participated in another clinical trial within 3 months of the study.
  • No use of any prescription medication within 14 days prior to the study.
  • No use of over-the-counter medication, herbal products, vitamins or minerals, within 7 days prior to the study.

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LL17035 | Malaria Study

Visit Schedule
*Appointments Only*

Participants will be required to attend 7 – 10 appointments. 

Part 1
Treatment (Week 1-52)
Part 2
Follow-up
Part 3 (Only if required)
Visit 2 3 4 5 6 7a 7b 8 9 10
Week 1 4 12 24 52 64 64 76 89 104
Hours 2-3 2 3-4 3-4 3-4 3-4 3-4 1-2 1-2 1-2
Payment $490 $700 $810 $880 $210 $210 $210

 

Participants who complete the study up to Week 64 will receive in total $2,880

Inclusion Criteria

  • Healthy males and females between the ages of 18 and 55
  • Must agree to stay in contact with the study site for the duration of the study and up to Week 64 (Visit 7b). Have no current plans to move away from Perth for the duration of the study
  • Must maintain a diary throughout the study
  • No eye conditions or use of prescription eye drops

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LE17092 | Toenail Study

Visit Schedule

8 Appointment Visits and 3 Follow-up Phone Call

Example Schedule:

Appointments Follow-up Phone Calls Final Visit
Day 1 Day 3 Day 7 Day 14 Day 42 Day 63 Day 84 Day 150 Day 210 Day 270 Day 365
5-6 hours 1-2 hours 10 minutes 1-2 hours

Testing a topical treatment for fungal nail infections.Participants will receive $675 for their time and inconvenience if they complete the study

 

Inclusion Criteria

  • Male & Females between the ages of 18 to 65 years old
  • BMI must be between 17.5 and 35.0 kg/m2
  • Participant must have onychomycosis (fungal nail infection) affecting at least one great toenail (the nail on your big toe)
  • Participant must be willing to refrain from the use of nail cosmetics throughout the study

 

 

 

Patient Studies

LL17125 | Coeliac Disease Study

Visit Schedule : CURRENTLY ON HOLD

Phases Screening Updosing Phase Maintenance Phase Follow Up Visit
Day Number Prior to Study Start  1  4  8 11 15 18 22 25 29 32 36 39 43 46 76
Approx. Visit Length (Hours) 8 5 1 8.5 1.5

 

Participants will receive $1200 (this payment is based on completing all dates from one of the trial’s cohorts).

  • Healthy Males and Females between the ages of 18 and 70
  • Have a diagnosis of Coeliac Disease confirmed with documentation (intestinal biopsy).
  • Have maintained Gluten-free Diet (GFD) for at least 12 consecutive months prior to screening.
  • Willing to consume a moderate amount of gluten (approximately 2 slices of wheat bread) at one time during the screening procedure.

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LE16071 | Non-Alcoholic Fatty Liver Disease (NAFLD) Study

Visit Schedule

Participants will be required to attend a screening visit, a liver ultrasound , a 3 night in-house stay, 4 x 1 night in-house stays, x MRI appointments & 6 x outpatient visits. 

Participants will receive $5,430 for their time and inconvenience if they complete the study.

Inclusion Criteria

  • Males and Females aged 18 to 65 years old
  • Must have a Body Mass Index (BMI) between 25-40kg/m2
  •  Weight must be stable (No more than 2.5kg of weight loss or gain in last 3 months)
  • Must have a diagnosis of Non-Alcoholic Fatty Liver Disease (NAFLD), or a liver ultrasound which shows at least 10% liver fat
  • Must have a diagnosis of Type 2 Diabetes OR Prediabetes (blood glucose > 5.7%)
  • Must be a non-smoker (for at least the last 3 months)

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LL17041 | C Diff Vaccine Study

Visit Schedule

Participants will receive 3 vaccination injections over a period of 6 months. There will be a total of 5 outpatient visits to attend, and 2 follow up phone calls across a period of 12 months.

Participants will receive $67 for each visit attended.

Inclusion Criteria

  • Males and females older than 60 years
  • BMI must be between 18-40 kg/m2
  • Must have an increased chance of future contact with healthcare systems by virtue of:
    • At least one inpatient hospitalisation of at least 2 nights in the last 12 months; or
    • At least 2 emergency room visits in the last 12 months; or
    • At least 10 outpatient visits (primary and/or secondary care visits) in the last 12 months; or
    • Taken antibiotics in the last 12 weeks; or
    • Residence in a nursing home

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